Results
| PMID | 20797704 |
| Gene Name | IL18 |
| Condition | Endometriosis |
| Association |
Associated |
| Mutation | IL-18 (-607 C607A) |
| Population size | 219 |
| Population details | 219 (135 women with endometriosis, 84 controls) |
| Sex | Female |
| Associated genes | IL-18 |
| Other associated phenotypes |
Endometriosis |
|
Fertil Steril. 2011 Jan;95(1):298-300. doi: 10.1016/j.fertnstert.2010.07.1046. Ayaz, Lokman| Celik, Sevim Karakas| Cayan, Filiz| Aras-Ates, Nurcan| Tamer, Lulufer Department of Biochemistry, School of Medicine, Mersin University, Mersin, Turkey. This study evaluated for the first time the relationship between interleukin-18 (IL-18) C607A genotypes and endometriosis in 135 women with endometriosis and 84 controls. In the study population, IL-18 -607 *A homozygote and A allele were positively correlated with the risk of developing endometriosis or the stage of endometriosis. Mesh Terms: Adult| Endometriosis/epidemiology/*genetics| Female| Gene Frequency| Genetic Predisposition to Disease/epidemiology| Genotype| Humans| Interleukin-18/*genetics| Middle Aged| *Polymorphism, Restriction Fragment Length| Promoter Regions, Genetic/g |
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